Surgical Treatment of Recurrent Peptic Ulcer Disease

Surgical treatment of peptic ulcer disease: current indications and techniques

Treatment of Peptic Ulcer Disease

For more than a century, peptic ulcer disease has been a major cause of morbidity and mortality. In the early part of the 20th century, when stress and diet were judged to be important pathogenetic factors for peptic ulceration, patients with peptic ulcers were treated with hospitalization, bed rest, and the prescription of “bland” diets. By the 1950s, investigators and clinicians had focused t...

The surgical treatment of peptic ulcer.

Drug Treatment of Peptic Ulcer Disease

Peptic ulcer disease is a widely prevalent upper gastrointestinal disorder worldwide. Gastric hypersecretion is recognized as the prime underlying cause of this disease. Earlier approaches towards alleviation of this disease have primarily focussed on symptomatic treatment of gastric hypersecretion with anti-secretory agents. Histamine H2 receptor antagonists represented the first successful me...

The acute complications of peptic ulcer and their surgical treatment.

It will be seen that three of the cases were under forty and two under forty-five. Except for one case, the length of history was measured in years. Seven of the eight ulcer-cancers occurred in the pyloric antrum, thus confirming that it is the chronic ulcer in this situation which is particularly liable to undergo malignant change. Five of the patients are dead, one was dying when last seen an...